What condition is most likely to show high spikes and slow-wave activity?

The condition that most likely shows high spikes and slow-wave activity is infantile spasms. This condition, also known as West syndrome, typically presents with a specific pattern of abnormal electrical activity in the brain characterized by hypsarrhythmia. Hypsarrhythmia is defined by irregular, high-amplitude spikes and slow waves on an electroencephalogram (EEG).

The high spikes in conjunction with slow-wave activity indicate a disorganized and chaotic electrical pattern, which is a hallmark of infantile spasms. These events typically occur in infants during the first year of life and can lead to developmental delays if untreated.

Other seizure types, while they may also show spikes on an EEG, do not characteristically present the same high spikes accompanied by the extensive slow wave activity as seen in infantile spasms. Understanding this unique EEG pattern is crucial for accurate diagnosis and treatment.