Which syndrome is characterized by electrical status epilepticus of sleep?

Landau-Kleffner syndrome is characterized by electrical status epilepticus of sleep (ESES), which is a condition where a child experiences ongoing seizure activity during sleep that can affect their cognitive and language development. This syndrome typically presents with the regression of language skills, behavioral issues, and the abnormal electroencephalogram findings that include slow wave activity and spikes during sleep. The electrical discharges correlate strongly with the clinical manifestations of seizures that occur predominantly in sleep, thereby making ESES a hallmark of this syndrome.

The significance of recognizing Landau-Kleffner syndrome lies in its impact on cognitive functioning and the necessity for tailored therapeutic strategies to mitigate seizures and support language development. Understanding ESES within this context is crucial for proper diagnosis and management, emphasizing its distinctive role in the syndrome's presentation.